human chorionic gonadotrophin

human chorionic gonadotrophin
= hCG
a hormone, similar to the pituitary gonadotrophins, that is produced by the placenta during pregnancy. hCG maintains the secretion of progesterone by the corpus luteum of the ovary, the secretion of pituitary gonadotrophins being blocked during pregnancy. Large amounts are excreted in the urine, and this is used as the basis for most pregnancy tests. Serum hCG monitoring is used for tracking early pregnancy and detecting ectopic pregnancies (in which the level will not double over a 48-hour period, as it does with normal pregnancies). The level of hCG in the serum is also one of the indicators used in prenatal screening tests: levels are higher in pregnancies affected by Down's syndrome in comparison with normal pregnancies (see also PAPP-A, triple test). Some malignant tumours (e.g. malignant teratoma, endodermal sinus tumour) secrete hCG, which can be used as a tumour marker. A preparation of hCG is given by injection to treat fertility problems due to ovulation disorders and to induce superovulation in in vitro fertilization.

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  • human chorionic gonadotrophin — noun hormone produced early in pregnancy by the placenta; detection in the urine and serum is the basis for one kind of pregnancy test • Syn: ↑human chorionic gonadotropin, ↑HCG • Hypernyms: ↑gonadotropin, ↑gonadotrophin, ↑gonadotropic hormone,… …   Useful english dictionary

  • human chorionic gonadotrophin — (HCG) a hormone, similar to the pituitary gonadotrophin that is produced by the placenta during pregnancy. Large amounts are excreted in the urine, and this is used as the basis for most pregnancy test. The level of HCG in the serum is one of the …   Medical dictionary

  • Human chorionic gonadotropin — chorionic gonadotropin, alpha polypeptide Identifiers Symbol CGA Alt. symbols FSHA, GPHa, GPHA1, HCG, LHA, TSHA …   Wikipedia

  • human chorionic gonadotropin — noun hormone produced early in pregnancy by the placenta; detection in the urine and serum is the basis for one kind of pregnancy test • Syn: ↑human chorionic gonadotrophin, ↑HCG • Hypernyms: ↑gonadotropin, ↑gonadotrophin, ↑gonadotropic hormone,… …   Useful english dictionary

  • human chorionic gonadotropin — noun a hormone produced by the placenta and fertilised egg after implantation in the wall of the uterus, used as an indicator for pregnancy testing. Abbrev.: HCG Also, human chorionic gonadotrophin …  

  • Гонадотропин Человеческий Хорионическии (Human Chorionic Gonadotrophin, Hcg) — секретируемый плацентой во время беременности гормон, сходный с гонадотропинами, которые вырабатывает гипофиз. В больших количествах этот гормон выделяется с мочой, что используется в качестве определяющего беременность фактора в большинстве… …   Медицинские термины

  • gonadotrophin — n. = GONADOTROPHIC HORMONE. * * * noun hormone secreted by the anterior pituitary gland and placenta; stimulates the gonads and controls reproductive activity • Syn: ↑gonadotropin, ↑gonadotropic hormone, ↑gonadotrophic hormone • Derivationally… …   Useful english dictionary

  • gonadotrophin — SYN: gonadotropin. [for g., fr. gonad + G. trophe, nourishment] * * * (gonadotrophic hormone) n. any of several hormones synthesized and released by the pituitary gland that act on the testes or ovaries (gonads) to promote production of sex… …   Medical dictionary

  • gonadotrophin — gonadotrophic hormone; n. any of several hormones synthesized and released by the pituitary gland that act on the testes or ovaries (gonads) to promote production of sex hormones and either sperm or ova. Their production is controlled by… …   The new mediacal dictionary

  • Chorionic gonadotropin beta — Chorionic gonadotropin, beta polypeptide PDB rendering based on 1hcn …   Wikipedia

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